منابع مشابه
Crossover interference
What is crossover interference? During prophase of meiosis in most eukaryotes, DNA recombination events between homologous chromosomes are induced to occur at high frequency, so there are usually multiple events per chromosome pair per meiosis. Whereas many of these recombination events are non-reciprocal, a subset results in reciprocal exchange of genetic material between chromosomes — crossov...
متن کاملCrossover interference in Arabidopsis.
The crossover distribution in meiotic tetrads of Arabidopsis thaliana differs from those previously described for Drosophila and Neurospora. Whereas a chi-square distribution with an even number of degrees of freedom provides a good fit for the latter organisms, the fit for Arabidopsis was substantially improved by assuming an additional set of crossovers sprinkled, at random, among those distr...
متن کاملCrossover interference in the mouse.
We present an analysis of crossover interference in the mouse genome, on the basis of high-density genotype data from two reciprocal interspecific backcrosses, comprising 188 meioses. Overwhelming evidence was found for strong positive crossover interference with average strength greater than that implied by the Carter-Falconer map function. There was some evidence for interchromosomal variatio...
متن کاملQuick guide Crossover interference
What is crossover interference? During prophase of meiosis in most eukaryotes, DNA recombination events between homologous chromosomes are induced to occur at high frequency, so there are usually multiple events per chromosome pair per meiosis. Whereas many of these recombination events are non-reciprocal, a subset results in reciprocal exchange of genetic material between chromosomes — crossov...
متن کاملCharacterization of human crossover interference.
We present an analysis of crossover interference over the entire human genome, on the basis of genotype data from more than 8,000 polymorphisms in eight CEPH families. Overwhelming evidence was found for strong positive crossover interference, with average strength lying between the levels of interference implied by the Kosambi and Carter-Falconer map functions. Five mathematical models of inte...
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ژورنال
عنوان ژورنال: The American Journal of Human Genetics
سال: 2003
ISSN: 0002-9297
DOI: 10.1086/376610